Volume 5, Number 1

The Journal of Applied Research

Table of Contents

1 PPAR-a Activation Attenuates Angiotensin II-Induced Vascular Inflammation, Arterial LDL Accumulation and Endothelial Layer Permeability in Mice
Doris M. Tham, PhD, Lening Zhang, PhD, Baby Martin-McNulty, Yi-Xin Wang, MD, Mark E. Sullivan, PhD, John C. Rutledge, MD

17 The Importance of a Syngeneic Glioma Implantation Model: Comparison of the F98 Cell Line in Fischer and Long-Evans Rats
David Mathieu, MD, Jacques B. Lamarche, MD, David Fortin, MD

26 Preclinical and Clinical Profile of Emmelle (Dextrin-2-Sulfate)—a Potential Anti-HIV Microbicide
Osmond J. D’Cruz, PhD, Fatih M. Uckun, MD, PhD

35 Integrating the Results of Phase IV (Postmarketing) Clinical Trial With Four Previous Trials Reinforces the Position that Regranex (Becaplermin) Gel 0.01% Is an Effective Adjunct to the Treatment of Diabetic Foot Ulcers
Martin C. Robson, MD, Wyatt G. Payne, MD, Warren L. Garner, MD, Joseph Biundo, MD, Vincent F. Giacalone, DPMI, Diane M. Cooper PhD, Peter Ouyang, PhD

46 Improved Appetite of Pregnant Rats and Increased Birth Weight of Newborns Following Feeding with Probiotic Lactobacillus rhamnosus GR-1 and Lactobacillus fermentum RC-14
Kingsley C. Anukam, PhD, Emmanuel O. Osazuwa, PhD, Gregor Reid, PhD

53 Phase I Trial of Concurrent Administration of Topotecan and Docetaxel for Cancer Treatment
D. Richard Ishmael, MD, Hong Liu, PhD, John A. Nordquist, MS, Robert E. Nordquist, PhD, Wei R. Chen, PhD

61 The Effect of Methylphenidate on Attention in Acquired Brain Injury as Recorded by Useful Field of View
Samir Al-Adawi, PhD, Ron Calvanio, PhD, Atsu S. S. Dorvlo, PhD,
Russell E. Costa, BSc, Jennifer J Mello, MS, CCC-SLP, Charlie C. Huynh, MD,
Mrugeshkumar K. Shah, MD, Heechin Chae, MD, David T. Burke, MD

73 Bioequivalence of Two Oral Formulations of Gatifloxacin Tablets in Healthy Male Volunteers
Marilyn Lockyer, Saleh Al-Dgither, Eman Al-Gaai, Ahmed Yousuf,
Muhammad M Hammami, MD, PhD

80 Autism and Autistic Symptoms Associated with Childhood Lead Poisoning
Theodore I. Lidsky, PhD, Jay S. Schneider, PhD

88 Serum Alkaline Phosphatase Level as a Prognostic Tool in Colorectal
Cancer: A Study of 105 patients
M. Wasif Saif, MD, Dominik Alexander, MSPH, Charles M. Wicox, MD

96 Sorbitan Monolaurate 20 as a Potential Skin Permeation Enhancer in
Transdermal Patches
Biswajit Mukherjee, MPharm, PhD, Kanupriya, MPharm,
Sushmita Mahapatra, MPharm, Surajit Das, BPharm, Balaram Patra, MPharm

109 Neuropharmacological Therapy of the Neuroendocrine Carcinoid
Syndrome: Report of Two Cases
Fuad Lechin, MD, PhD, Bertha van der Dijs, MD, Beatriz Orozco, MD, Simon
Rodríguez, MD, Scarlet Baez, MD

115 Evaluation of Porcine Small Intestinal Submucosa in Achilles Tendon Repair
Fernando H. Greca, MD, PhD, Eduardo J. B. Ramos, MD, PhD,
Vanessa C. Dallolmo, MD, Antonio P. G. Silva, MD, Wilson H. Mima, MD, Luciano
Okawa, MD, Tiago G. Alencar, MD

124 Combined Diet and Low-Impact Aerobic Exercise Program: Impact on
Weight, Girth, and Muscular Strength, Part 1
Jerrold S. Petrofsky, PhD, JD, Amy Morris, BS, Julie Bonacci, BS, Rachel Jorritsma,
BS, Ashley Hanson

136 Muscle Use During Low-Impact Aerobic Exercise (Gliding) Compared to
Conventional Weight Lifting Equipment, Part 2
Jerrold S. Petrofsky, PhD, JD, Jennifer Hill, BS, Ashley Hanson,
Amy Morris, BS, Julie Bonacci, BS, Rachel Jorritsma, BS

149 Randomized, Double-Blind, Crossover Comparison Between
Two Levocetirizine Formulations on Histamine-Induced Cutaneous
Response in Healthy Male Human Adult Volunteers
P Usharani, DNB, MD, MUR Naidu, MD, KLN Reddy, PhD, BPS Reddy, PhD,
T Ramesh Kumar, MD

160 Muscle Use During Exercise: A Comparison of Conventional Weight
Equipment to Pilates With and Without a Resistive Exercise Device
Jerrold S. Petrofsky, PhD, JD, Amy Morris, BS, Julie Bonacci, BS,
Ashley Hanson, Rachel Jorritsma, BS, Jennifer Hill, BS

174 Dikmengil Technique for Proximal Anastomosis of Saphenous
Vein to Aorta Using Hegar Dilator Without Clamping
Murat Dikmengil, MD, Murat Ozeren, MD, Barlas Aytacoglu, MD, Nehir Sucu, MD

177 Assessment of the Static Component of Aerobic Exercise: A Comparison
of Exercise Using Cycle and Treadmill Ergometry, Hip Extension Exerc i s e s
With or Without Gliding, and Gliding Video Workouts
J e r rold S. Petrofsky, PhD, JD, Jennifer Hill, BS, Ashley Hanson, Amy Morris, BS
Julie Bonacci, BS , Rachel Jorritsma, BS

193 Meprobamate Withdrawal After Forty Years of Drug Treatment
AMA Shehab, MBChB, MRCP, DipMEd, MMEd, DM, A Khanbhai, MBChB, MRCP, AK
Gupta, MBBS, DM (medicine), DM (psychiatry), RE Ferner, MBBS, MSc, DM, FRCP

196 Hemorrhagic Shock and Bacterial Translocation - Contact Publisher
Ahmet Çelik, MD, Söhret Aydemir, MD, Murat Alkanat, MD, Sara Habif, MD, Ahmet
Keskinoglu, MD, Dilek Erdener, MD

206 Stimulatory Effect of the Aqueous Extract of Ruta chalepensis on the Sex
Organs and Hormones of Male Rats
Aly Abdullah Al Qarawi, PhD

212 Anti-proliferation and Apoptosis Induced by Selective COX-2 Inhibitor in
Human Esophageal Squamous Carcinoma Cells
Hong-Ping Yu, PhD, Xiao-Li Wang, MD, Yan-Hua Su, MD, Yuan-Yuan Li, MD, Fang Li,
MD, Shun-Qing Xu, PhD

221 Liposomal Delivery of Antileishmanial Agents
Mukul Kumar Basu, PhD